I have bought several items from Newegg that were open box 3 Hard Drives, a monitor, Heatsink and fan, and a few others. I have had no problems with them at all. The oldest item 1 of the 3 hard drives was bought 3 yrs ago and has been running 24/7. The only think you MUST be aware of though are open box items are/may not have all the cables manuals or software that would normally come with an unopened box. And always Newegg is hard to beat.
jd