These Programs will let you open and view the contents, as well as modify the contents and make ISO's:
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WinISO- M
MagicISO-
UltraISOThese ones only let you view the contents:
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ISOBuster (also lets you make ISO's)
Free!-
Daemon Tools (also works very well for mounting an image)
Free!I know that
WinRAR and
WinACE let you open ISO files, but I have never used them for this purpose, so I can't say if you can safely modify an ISO file.
(Although you should always be curefull when changing an ISO file...)