when i change the mouse sensitivity setting i cant use the mouse wheel to change weapons anymore

i used to get this too

install the 1.32 patch
run quake3 change mouse settings, quit quake3
run quake3, see if you can assign it now?

its quite a weird bug.. just seems to go after a while

Hav'nt played Q3 in a while, but I used to get this issue regular where settings didn't "stick".

If the above suggestion doesn't work then;

1. Open "q3config.cfg" in your text editor (Notepad or such NOT Word)
2. Scroll down till you see

make sure it's as you want.
3. Save the file and close editor.
4. set the attributes on the file to "Read only"

is there a setting for mouse sensetivity there as well?