I now this is in old topic, but certainly not redundant as so many folks still use Photodraw. I found this problem to be more a file size issue rather than a DPI issue although reducing DPI does also reduce file size. In my case, I have found that by reducing the file size by way of reducing the picture size, Photodraw is happy. Example ... Original Photo - Will not open in Photodraw 4000x2307 Pixels DPI 72 File size 5.6Mb Resized Photo - Will open in Photodraw 2401x1385 Pixels DPI 72 File size 2.97Mb I found that by keeping the file size below 3Mb I do not have anymore problems. My camera is a Nikon D3100. As with gabumoon, I started using Photoshop due to this problem with Photodraw, but after finding out the problem - just use Photoshop to re-size using a fractal resizer plugin and then continue with Photodraw. Where Photoshop is far more powerful, I find Photodraw fits my requirements better. Hope this helps someone ADDED: Found this which I have applied and works perfectly now - no resize required. Apparently this is an Official Microsoft Fix * Graffics Filter file JPEGIM32.FLT has been damaged, corrupted, or is missing entirely, possibly as a result of some software overwriting the correct version, which they are apparently unwilling to specify. Their solution is to rename the filter file (in the C:\Program Files\Common Files\Microsoft Shared\Grphflt\ directory) with a .old extension and reinstall the correct version either from the Office CD or the OS CD.