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The res:// URI scheme just tells Windows to open the specified file (ieframe.dll, under System32) and retrieve the specified resource name ("info_48.png"). Note that res:// hides the new MUI system (so it also checks system32\en-US\ieframe.dll.mui).
The INFO_48.PNG resource exists (on my computer, at least) as C:\Windows\system32\en-US\ieframe.dll.mui\HTML\"INFO_48.PNG"