Cannot open folders

[kernelcored]

Well, one of my staff's computer at the office has this weird problem. We found out that, somehow we can't open My Computers, My Documents, Control Panel and to make it short, we cannot open any folders at all.

I've scanned the computer with SpyBot, Ad-aware, Symantec AV 10, About:Blaster and Spyware Doctor, but it seem that the problem still persists.

Whenever we double click or right-click>'open' on any of the folders, we can only see a few second of hourglass and then no response or whatsoever from the system. It just went completely.. errr.. nothing. Please help us.

Oh, i've googled the forum and unfortunately, found nothing that might be relevant to my case.